Lisa » Novel approaches such as stem cell therapy ar

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Our eyes are one of the most valuable sense organs that enable us to see this beautiful and colourful world. Many of us face eye problem at a time or other like itching, blurring or fatigue. Some of the eye problems are minor and goes away easily; however some are serious eye diseases and one of them is Leber鈥檚 Hereditary Optic Neuropathy (LHON). It is the most common inherited genetic disorder that leads to vision loss and mainly affects young males typically between 12 and 30 years of age.

Cause


Leber鈥檚 hereditary optic neuropathy is an inherited optic neuropathy caused due to mutations in the mitochondrial DNA. These mutations cause abnormalities in the structure of proteins affecting cellular respiration. The impaired cellular respiration impedes the function of nerve cells present in retina, leading to loss of vision.


Symptoms


The person diagnosed with LHON may initially be asymptomatic or just have mild blurring of central visual field. The central vision is especially required for tasks such as reading Wholesale Soccer Jerseys Cheap , driving and recognizing faces. It typically begins with one eye, with sequential involvement of the fellow eye later. The visual acuities of LHON patients are typically 20200 or worse.


In addition to vision loss, the symptoms of LHON person may include movement disorders, tremors, and impaired electrical signals that control the heartbeat (cardiac conduction defects). Some affected individuals can also have features similar to multiple sclerosis, characterized by muscle weakness Wholesale Soccer Jerseys Free Shipping , poor coordination and numbness.


Treatment


There is no established treatment available for LHON. In few cases, the central vision gradually gets improved; however in most of the cases the vision loss is profound and permanent. Treatment options are few that include mitochondrial cocktails, ubiquinone analogues, steroids, immunosupressants with limited benefit. Medications having antioxidants have also shown some positive results in reducing the neurotoxic stress occurred due to reactive oxygen species. Patients are advised to avoid neurotoxins such as tobacco and alcohol because of their tendency to increase oxidative stress. Vision aids ( such as magnifiers, large-print devices) may also be helpful.


Stem cell therapy


Novel approaches such as stem cell therapy are being explored for management of LHON. Stem cells being smart cells of body have ability to regenerate nerve cells in the optic region Wholesale Soccer Jerseys From China , allowing eye patients to recover some vision. The stem cell therapy procedure for eye disease include collection of tissue from patient, isolation of stem cells and injecting back stem cells to patients at retrobulbar site. Once the stem cells are administered to the retrobulbar space they begin to home at damaged tissue signals and start repairing damaged nerves. These stem cells. Adidas NMD For Sale Cheap Air Max Shoes Cheap Air Max Outlet Cheap Air Max Mens Shoes Cheap Air Max Womens Shoes Cheap Air Max Womens Cheap Air Max Mens Cheap Nike Air Max Black Nike Air Max Sale Free Shipping Nike Air Max Mens Sale